BIOL-335   Cell Physiology

A study of the function of animal cells with emphasis on events occurring outside the nucleus. Major emphases include the structure of the cell membrane, functions and interrelationships of membrane transporters and ion channels, synthesis of proteins and targeting of vesicles through the secretory pathway, structure and function of cell surface receptors and their interactions with intracellular signaling pathways, mechanisms of cell motility, and interactions of cells with the extracellular matrix. Concepts will be discussed in the context of historical development, examination of experimental evidence and relationship to the function of tissues and organs. Lectures, problem-based discussions of the primary literature, laboratories. Prerequisites: Biology 224 (or 141) and 225, Chemistry 253 (or 261 and 262); Completion of Biology 206 or Biology 331 highly recommended.